Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic (BIO-IRA)

Grenoble Alpes University Hospital Center (CHU)

Status: Completed

Conditions: Acute Respiratory Insufficiency

Study type: Observational

Funder types: Other

Identifiers

NCT00835809

0811

2008-A00703-52 (Registry Identifier)

Details and patient eligibility

About

Biomarkers have an interest in clinic diagnostic ,therapeutic and prognosis in pathophysiologic situation including cardiovascular.But interest of biomarkers in diagnostic care of severe acute respiratory insufficiency remains to clear.

We propose to determine the more relevant marker combination in this case.

Full description

In urgence of a severe acute respiratory insufficiency,for thanks to an approach diagnostic, therapeutic and prognostic we propose to determine the more relevant biomarker combination.

An expert committee will compare the biomarker diagnostic and prognostic relevance thanks to all elements clinico-biological and patient monitoring.

Enrollment: 400 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Oxygen saturation below or equal to 92% in ambient air.
• Respiratory frequence above 25 cycle per minute

Exclusion criteria

• Minors
• Pregnant or lactating women
• Patient without social security
• Patient hospitalize without consent
• Chest pain with acute coronary electro-cardiographic change leading immediate achievement of a diagnostic coronary angiography and/or therapeutic
• Pneumothorax

Trial design

400 participants in 1 patient group

Acute respiratory diseases.

Description:

Patient admit in emergency or intensive care unite with acute respiratory insufficiency.