Multi-morbidity Screening in People With Type 2 Diabetes and Pre Diabetes

University of Liverpool

Status: Active, not recruiting

Conditions: Pre Diabetes; Heart Failure; Type 2 Diabetes; Non-Alcoholic Fatty Liver Disease; Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT06053177

UoL001691

Details and patient eligibility

About

People with type 2 diabetes are at risk of complications linked with high blood sugars and these are monitored for in healthcare appointments. However, people with type 2 diabetes commonly suffer with additional health conditions that can affect the liver, heart and their breathing while sleeping. These conditions are thought to be caused by a similar underlying process that causes type 2 diabetes, as a result they are very common in people type 2 diabetes. Despite this they are not part of the routine health check for these people. Worryingly, current research suggests that the risk for developing these health problems, and direct complications of type 2 diabetes, can start at blood sugar levels below the threshold of type 2 diabetes. In a group of people said to have prediabetes. These people do not currently undergo annual healthcare appointments to monitor for these health complications or other linked health conditions.

This study aims to pilot a new style of clinic to address these issues. The investigators will perform a multi-morbidity assessment, where they will look for several different health problems at the same time. The investigators will be looking at health problems linked with high blood sugars, this will include problems with the liver, heart, nerves, eyes, and participants breathing overnight. They have developed a clinic visit which uses questionnaires, simple examination techniques and modern devices to try and identify these health problems.

An important part of healthcare is the burden it places on people with health problems, with this in mind the investigators will be giving the people involved in their study a voice to try and direct future research and healthcare, the investigators will ask them to provide feedback on their experience in taking part in the study and what their thoughts are in undergoing a longer but more comprehensive health appointment.

Enrollment: 400 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Type 2 diabetes study group

• Participants with a documented diagnosis of type 2 diabetes or HbA1c ≥48mmol/mol.
• Age ≥18 years

Prediabetes study group

• HbA1c 42 - 47 mmol/mol (inclusive) or enrolled in the diabetes prevention programme.
• Age ≥18 years

Exclusion criteria

• Type 1, 3 or Maturity onset diabetes of the young.
• Participants who are pregnant at the time of screening
• Unable to give informed consent

Trial design

400 participants in 2 patient groups

Type 2 Diabetes

Description:

Participants with type 2 diabetes

Pre Diabetes

Description:

Participants who's most recent HbA1c is in the prediabetes range.