Multicenter Clinical Trial of Buprenorphine - 3

University of California, Los Angeles (UCLA)

Status and phase: Completed; Phase 3

Conditions: Opioid-Related Disorders

Treatments: Drug: Buprenorphine

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00000207

R18DA006082 (U.S. NIH Grant/Contract)

NIDA-06082-3

R18-06082-3

Details and patient eligibility

About

The purpose of this study is to test the efficacy and safety of buprenorphine.

Full description

12 different sites for a total of 736 subjects (60 at Pizarro, 70 at West LA Tx center, 15 in the 1 year extension)

Sex: All

Ages: 21 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

M/F, ages 21-50. opiate dependence according to DSM-IV criteria. Self-reported use within the last 30 days. Agreeable to conditions of the study and signed informed consent.

Exclusion criteria

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative-hynotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.