Multicenter International Trial Ring AnnulopLasty (MITRAL)

Abbott

Status

Completed

Conditions

Mitral Valve Insufficiency

Treatments

Device: mitral valve repair (SJM® Rigid Saddle Ring)

Study type

Interventional

Funder types

Industry

Identifiers

NCT00727012

CS06003RG

Details and patient eligibility

About

This clinical study is a multicenter, prospective non-randomized observational study without concurrent or matched controls in which 150 patients receiving an SJM® Rigid Saddle Ring will be included. The primary objective of the study is to demonstrate the effectiveness of the SJM® Rigid Saddle Ring when used in mitral valve repair procedures.

Enrollment

180 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient requiring a mitral valve repair due to mitral degenerative or functional disease (Note: Patients that underwent concomitant procedures, e.g. coronary artery bypass grafting, are eligible for this study);
Patient (or legal guardian) has signed a study specific informed consent form agreeing to the data collection and follow-up requirements;
Patients are at least 18 years old.

Exclusion criteria

Patient requires replacement of the aortic, tricuspid or pulmonary valve or has a pre-existing prosthetic valve;
Patient is pregnant or nursing;
Patient has active endocarditis;
Patient is actively participating in another study of an investigational drug or device;
Patients unavailable to follow-up visit (abroad residents, patients affected by neurological disorders...);
Patients who are intravenous drug abusers, alcohol abusers, prison inmates or unable to give informed consent;
Patients with a major non-cardiac evolving disease;
Patients with a life expectancy less than 1 year;
Patients are known to be noncompliant or are unlikely to complete the study;
Any case in which mitral annuloplasty rings are not indicated;