Multicenter Pediatric Low-Dose CT Protocol: Development and Clinical Verification
Status
Conditions
Treatments
Study type
Funder types
Identifiers
Details and patient eligibility
About
Children are sensitive to ionizing radiation, and there are significant regional variations in current pediatric CT radiation doses. Although there are studies on low-dose CT targeting single lesions, these studies require clear clinical indications and support from advanced equipment, making widespread promotion difficult. The establishment of low-dose CT protocols is mostly experience-based; when radiologists lack confidence in image quality, the credibility of diagnostic reports is compromised. Therefore, the development of low-dose protocols must meet the diagnostic confidence of most radiologists, enable clear visualization of key anatomical structures in clinical practice, and satisfy the requirements for disease diagnosis.
The purpose of this study is to establish a pediatric low-dose CT scanning protocol using Low-dose Simulation of CT (LDS) technology, and conduct a multicenter randomized controlled trial (RCT) in clinical settings to verify the clinical feasibility of this low-dose CT scanning protocol.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Aged 0-17 years.
- Pediatric patients for whom a CT examination is deemed necessary by an attending physician.
Exclusion criteria
- Parents/guardians refuse to consent to low-dose CT examination.
- Pediatric patients are in critical condition, with no time allocated for explanation of the randomized controlled trial (RCT) protocol.
Trial design
Primary purpose
Allocation
Interventional model
Masking
2,650 participants in 2 patient groups
Trial contacts and locations
Loading...
Central trial contact
Jihang Sun, MD
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal