Multicenter Registry on Microvascular Dysfunction - Searching a New Ach Spasm Definition (MICRO-SNAPE)

Johannes Gutenberg University (JGU)

Status: Enrolling

Conditions: Coronary Vasospasm; Coronary Microvascular Disease

Treatments: Diagnostic Test: Coronary physiology assessment

Study type: Observational

Funder types: Other

Identifiers

NCT06125392

UM 20-0274

Details and patient eligibility

About

The MICRO-SNAPE registry will collect data from patients undergoing investigation of microvascular dysfunction and coronary spasm in Europe and North America.

Full description

Microvascular dysfunction is an important determinant of patients´quality of life and prognosis, which however remains poorly classified. Given the high burden of disease and the severity of the functional impairment in these patients, the lack of a clear understanding and diagnosis has a potentially large clinical importance. It is therefore important to better describe the phenotype of these patients. The MICRO-SNAPE registry will allow investigating these associations. Patient data as collected during the local clinical practice and at the operator's discretion, will be retrospectively entered in this non-interventional registry in anonymous form.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who underwent combined measurements of coronary pressure and flow in at least 1 native coronary artery in response to endothelium dependent and independent vasodilators.

Exclusion criteria

• Hemodynamic instability
• Age <18 years

Trial design

1,000 participants in 1 patient group

Invasive assessment of coronary vasomotor function

Description:

All lesions undergoing assessment of coronary microvascular dysfunction and coronary spasm using coronary pressure wires.

Treatment:

Diagnostic Test: Coronary physiology assessment