Multicenter Retrospective Study of Isoflurane in Refractory and Super-Refractory Status Epilepticus (I-Seizure)

Hopital of Melun

Status: Completed

Conditions: Refractory Status Epilepticus

Treatments: Drug: Isoflurane

Study type: Observational

Funder types: Other

Identifiers

NCT05830864

MIR-2023-01

Details and patient eligibility

About

Isoflurane might be used as anticonvulsive therapy in refractory status epilepticus. The aim of the study is to assess the efficiency of Isoflurane in this indication.

Full description

Investigators will collect in 4 ICUs the data from consecutive patients hospitalized between january 2016 and january 2023. Included patient were those treated by Isoflurane for refractory status epilepticus.

Enrollment: 66 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years, hospitalized in ICU between 2016-01-01 and 2023-01-01, suffering refractory status epilepticus treated by inhaled Isoflurane as third anticonvulsive therapy

Exclusion criteria

• post-anoxic refractory status epilepticus after cardiac arrest, withdrawal of consent for medical data use

Trial design

66 participants in 1 patient group

Main cohort

Description:

Adult patients with refractory status epilepticus treated by Isoflurane as third anticonvulsive therapy

Treatment:

Drug: Isoflurane