Multicenter Validation of the PREDICT Score

Mansoura University

Status: Completed

Conditions: Rectal Cancer

Treatments: Diagnostic Test: PREDICT score

Study type: Observational

Funder types: Other

Identifiers

NCT05078515

Mansoura2020110

Details and patient eligibility

About

Even after adequate TME with grade III mesorectal grading, local recurrence remains a possible event. Several studies investigated different parameters and assessed their predictive power in regards to local recurrence after TME. These parameters included a variety of patient-related, tumor-related, and treatment-related factors. A recent meta-analysis reviewed the current literature for the predictors of local recurrence after TME for rectal cancer and developed a prognostic scoring system, the PREDICT score.

The present study aimed to validate the PREDICT scoring system by applying it to a prospective cohort of patients with rectal cancer who underwent curative TME in three

Enrollment: 262 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients of either sex with non-metastatic low or middle rectal cancer who underwent elective TME with curative intent

Exclusion criteria

• Patients with recurrent or metastatic rectal cancer at the time of presentation
• Patients with synchronous colon cancer
• Patients with missing data on the outcome of TME.

Trial design

262 participants in 2 patient groups

Patients with recurrence after TME

Description:

Patients who developed local recurrence after TME of rectal cancer

Treatment:

Diagnostic Test: PREDICT score

Patients without recurrence after TME

Description:

Patients who did not develop local recurrence after TME of rectal cancer

Treatment:

Diagnostic Test: PREDICT score