Multicentre ObseRvational Study in Posterior mecHanical thrombEctomy: conscioUs Sedation vs General aneSthesia

Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta

Status: Completed

Conditions: Conscious Sedation; General Anesthesia; Posterior Circulation; Mechanical Thrombectomy

Treatments: Procedure: Type of anesthesia choice

Study type: Observational

Funder types: Other

Identifiers

NCT05082896

MORPHEUS STROKE REGISTRY

Details and patient eligibility

About

The association of conscious sedation vs. general anesthesia in ischemic stroke with posterior circulation occlusions undergoing endovascular therapy, is istill unknown.

No prospective or clinical trials have studied this effect on posterior circulation strokes.

The choice of anesthetic regimen is ussually depending on local stroke-team protocols or neurointerventional preference.

MORPHEUS Stroke Registry is a prospective multicentre observational study that investigates the association between anestheisa and functional outcome in patients with posterior circulation large vessel occlusion treated endovascularly.

Enrollment: 453 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject aged ≥ 18 years
• Evidence of posterior arterial occlussion (basilar artery, intracranial vertebral artery and posterior cerebral artery)
• Patients eligible for mechanical thrombectomy

Exclusion criteria

• Patient's refusal to participate
• Arterial recanalization prior to endovascular thrombectomy attempt
• Patient unable to present or be available for follow-up

Trial design

453 participants in 2 patient groups

Conscious Sedation

Treatment:

Procedure: Type of anesthesia choice

General Anesthesia

Treatment:

Procedure: Type of anesthesia choice