Multidetector Raw CT as a Single Tool in the Setting of Ischemic Stroke (COCASE)

Civil Hospices of Lyon

Status: Completed

Conditions: Ischemic Stroke

Treatments: Device: Multidetector raw CT

Study type: Interventional

Funder types: Other

Identifiers

NCT00708188

2006.431/24

Details and patient eligibility

About

This is a prospective study including acute ischemic stroke patients aged 18 to 90. Multidetector raw CT is performed in acute ischemic stroke patients. Heart, neck vessels and brain arteries are studied during the same acquisition. Results are compared with the standard methods including transesophageal echocardiography (TEE), Doppler ultrasound (DUS) and MR angiography (MRA) of neck vessels. The main criteria is the ability of CT to classify the stroke etiology correctly according to the TOAST classification in comparison with the standard methods.

Enrollment: 49 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute (< 1 week) ischemic stroke patient aged 18 to 90
• Informed consent obtained
• Presence of health insurance

Exclusion criteria

• Pregnancy or absence of efficient contraceptive method
• Allergy
• Allergy to contrast material
• Asthma
• Renal failure (blood creatinine > 130 µmoles/l, creatinine clearance < 80 ml/mn according to Cockroft method)
• Myeloma
• Hyperthyroidism (uncontrolled)
• Difficulties to synchronize CT to heart rhythm
• Contra-indication to TEE or MRI
• Absence or retirement of informed consent
• Absence of health insurance

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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49 participants in 1 patient group

Multidetector raw CT

Experimental group

Treatment:

Device: Multidetector raw CT