Multidimensional Burden of Platinum Resistant Ovarian Cancer (PROC) on Patients and Caregivers in Canada

PeriPharm

Status: Invitation-only

Conditions: Caregiver Burden; Patient Burden; Ovarian Cancer

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT07035067

Ovarian Cancer

Details and patient eligibility

About

Filling the gap in Canadian evidence on the burden of PROC on QoL is essential. It will help better understand the impact of PROC on multiple aspects of the lives of patients and their caregivers and the real-life hurdles faced by PROC patients and their caregivers. The outputs of this study will help better understand the hurdles and challenges they face and the significant unmet medical need.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Patient Inclusion Criteria

1. ≥18 years old
2. Patients with PROC who received >1 prior line of therapy identified through a screening survey. PROC will be defined as recurrence less than 6 months after last platinum chemotherapy (i.e. carboplatin or cisplatin)
3. Ability to read and understand French or English
4. Signature of ICF

Patients Exclusion Criteria

1. Patients with PSOC, defined as those who:

   1. Have not progressed within less than 6 months after completion of platinum-based chemotherapy or;
   2. Are still on platinum chemotherapy or;
   3. Receive maintenance therapy.

2. Patients with platinum-refractory ovarian cancer, defined as not responding or disease progressing during therapy or within three months after the last dose

Caregivers Inclusion Criteria:

1. ≥18 years old
2. Current caregiver of a patient with PROC (see definition to be used above) who received >1 prior line of therapy identified through a screening survey.
3. Ability to read and understand French or English
4. Signature of ICF.

Caregivers Exclusion Criteria:

1. Caregivers of patients with PSOC (see definition above)
2. Caregivers of PROC patients who have passed away
3. Caregivers of platinum-refractory patients (see definition above)

Trial design

150 participants in 2 patient groups

Patients with PROC part of Ovarian Cancer Canada mailing lists

Treatment:

Other: No intervention

Caregiver of PROC patients part of Ovarian Cancer Canada mailing lists

Treatment:

Other: No intervention