Multidimensional Measurement of Psychopharmacological Treatment Response

Child Psychopharmacology Institute

Status: Completed

Conditions: Sleep Disorders; Attention Deficit Disorders; Mood Disorders; Autism Spectrum Disorders

Treatments: Drug: Pharmacological Intervention

Study type: Observational

Funder types: Other

Identifiers

NCT01184235

Act3

Details and patient eligibility

About

The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.

Full description

Baseline actigraphic measurements, multi-symptom operationally defined observations and psychometric data will be established and repeated to measure treatment response. Additional biological and biometric measures that have potential to further characterize the cohorts under study or treatment response will be collected as practical and when possible.

Enrollment: 44 patients

Sex: All

Ages: 6+ months old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosis of:
• Autism Spectrum Disorder
• Mood Disorder
• Attention Deficit Hyperactivity Disorder
• Unaffected First Degree Relative of Study Subject
• Anticipation of pharmacological intervention or current pharmacological intervention

Exclusion criteria

Inability to wear an actigraphy watch

Trial design

44 participants in 4 patient groups

Autism Spectrum Disorders

Description:

This group will include those receiving or anticipating receiving pharmacological intervention whose primary diagnosis is Autism Spectrum Disorder

Treatment:

Drug: Pharmacological Intervention

Attention Deficit Hyperactivity Disorder

Description:

This group will include those receiving or anticipating receiving pharmacological intervention whose primary diagnosis is Attention Deficit Hyperactivity Disorder.

Treatment:

Drug: Pharmacological Intervention

Unaffected 1st Degree Relatives

Description:

This group will include unaffected, non treated first degree relatives of this study's subjects receiving or anticipating receiving pharmacological intervention.

Mood Disorders

Description:

This group will include those receiving or anticipating receiving pharmacological intervention whose primary diagnosis is mood disorder.

Treatment:

Drug: Pharmacological Intervention