Multidisciplinary and Personalized Care of Behavioral Disorders in Frontotemporal Lobar Degeneration. (DLFT)

University Hospital of Bordeaux

Status: Completed

Conditions: Frontotemporal Lobar Degeneration

Treatments: Other: 3 Home visits made by a psychologist

Study type: Interventional

Funder types: Other

Identifiers

NCT03606798

CHUBX2015/06

Details and patient eligibility

About

Fronto-Temporal Lobar Degeneration (FTLD) refers to 3 categories of neurodegenerative diseases generally occurring between 55 and 65 years: Fronto-Temporal Dementia(FTD), Primary Progressive Aphasia (PPA), Semantic Dementia (SD). Clinical expression is substantially variable among individuals, but in most cases, behavioural disorders and personality changes are prominent. FTLD is poorly known by general public including health care professionals. Currently, the French health system does not meet the needs and expectations of patients and their families

Full description

Patients with FTLD and their caregivers need to be recognized and supported through specific and tailored made actions provided by expert teams. The main objective of our study is to evaluate the effectiveness of a 6-month personalized multidisciplinary care provided to the dyad FTLD patient and caregiver on patient's behavioural disorders. The secondary objectives are to assess the impact of this program on patient's cognitive deterioration, functional autonomy and behavioral problems, as well as caregiver's depressive symptomatology and sense of competence

Enrollment: 38 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria:

Patients

• Fronto-Temporal Lobar Degeneration diagnoses
• Men or women aged 18 and over

Caregiver

• Spouse, brother, sister, child living at patient's home and can provide the medical team of reliable information on the status of their parent.

Exclusion criteria :

Patient

• Patient institutionalized
• Pregnant or breast-feeding woman
• Psychotic syndrome
• Severe and unstable general medical condition
• Patient bedridden

Caregiver

• Persons under legal protection
• Severe and unstable general medical condition
• Pregnant or breast-feeding woman

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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38 participants in 2 patient groups

Multidisciplinary and personalized care

Experimental group

Description:

Personalized care and proposals bring by a team of experts : neurologists ; geriatrician ; psychologist.

Treatment:

Other: 3 Home visits made by a psychologist

Reference care

No Intervention group

Description:

Standard clinical evaluations of patient with Frontotemporal Lobar Degeneration.