Multidisciplinary Approach to Reduce Injury and Substance Abuse

The University of Texas System (UT)

Status and phase: Completed; Phase 3

Conditions: Drug Abuse

Treatments: Behavioral: Brief Intervention; Behavioral: Brief Intervention plus Booster; Behavioral: Brief advice

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01048359

DESPR DA026088

5R01DA026088-02 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The primary purpose of the project entitled: Multidisciplinary Approach to Reduce Injury and Substance Abuse, which is funded by the National Institute on Drug Abuse (5R01DA026088-02), is to compare the effectiveness of brief intervention, brief intervention plus a booster, and brief advice for adult patients who abuse drugs and present to a trauma department for treatment of an injury.

Full description

Multidisciplinary Approach to Reduce Injury and Substance Abuse is a randomized clinical trial evaluating the effectiveness of brief advice (BA), brief motivational intervention with feedback (BMI), and brief motivational intervention with feedback and booster (BMI+B) in injured patients with drug problems.

The setting is a level 1 Trauma Department, which serves a large and diverse patient population. Injured patients are screened for eligibility in the project based on a positive toxicology screen or self reported drug use in the past 90 days. The primary outcome of interest will be patients' subsequent drug use. Other outcomes of interest include: HIV-related risk behaviors, improved health outcomes (including injury reduction), increased employment, decreased engagement in illegal behavior, increased substance abuse treatment utilization, and enhanced quality of life at three, six, and twelve month follow-ups.

This study will also examine the potential moderating and mediating effects of patient readiness to change, use of experiential and behavioral processes of change and decisional balance considerations. In addition, this project will examine implementation factors at the organizational level and the cost effectiveness of BA, BMI, and BMI+B.

Study participants and their related identifying information will be collected during the time they are admitted to the recruitment hospital trauma department. Study participants must be 18 years or older, speak English or Spanish, have been admitted to the recruitment hospital trauma department, and test positive for illegal drugs or admit to illegal drug use when verbally screened. Additional information will be collected from participants in the in-person assessment interviews at three, six, and 12 month follow-up periods.

Enrollment: 417 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Study participants must be 18 years or older
• Speak English or Spanish
• Been admitted to the level 1 Trauma Department
• Test positive for illegal drugs or admit to illegal drug use

Exclusion criteria

• Other penetrating trauma not related to motor vehicle collisions, violence or falls, such as poisoning and, bites
• Patients with traumatic brain injury, or a Glasgow Coma Scale score of less than 15
• Patients who do not pass the Mini-Mental Status Exam are excluded

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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417 participants in 3 patient groups

Brief Intervention

Experimental group

Description:

30-45 minute motivational interviewing based intervention with feedback addressing drug use, injury prevention and HIV risk.

Treatment:

Behavioral: Brief Intervention

Brief advice

Active Comparator group

Description:

This condition of the experiment acts a control and will be a short session in which the therapist will provide brief advice about drug use and give the patient a pamphlet.

Treatment:

Behavioral: Brief advice

Brief Intervention plus Booster

Experimental group

Description:

30-45 minute motivational interviewing based intervention with feedback addressing drug use, injury prevention and HIV risk plus a brief phone booster session at 1 month post-intake to review feedback, 2) assess progress, 2) renew motivation to change, and 3) evaluate and affirm commitment to change.

Treatment:

Behavioral: Brief Intervention plus Booster