Multifocal Electrophysiologic Findings After Intravitreal Bevacizumab(Avastin)Treatment

Asociación para Evitar la Ceguera en México

Status and phase: Terminated; Phase 3; Phase 2

Conditions: Choroidal Neovascularization; Vascular Vein Oclussion; Diabetic Proliferative Retinopathy

Treatments: Drug: Intravitreal Bevacizumab

Study type: Interventional

Funder types: Other

Identifiers

NCT00417833

APEC-0017

Details and patient eligibility

About

Purpose: Determine the short-term safety of intravitreal bevacizumab by multifocal electroretinography (mf-ERG).

Methods: 120 eyes with choroidal neovascularization, proliferative diabetic retinopathy and retinal vein occlusion received intravitreal bevacizumab (2.5mg/0.1cc). All patients underwent best corrected visual acuity, fluorescein angiography, optical coherent tomography and mf-ERG before and 1 month after treatment.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Proliferative diabetic retinopathy, vascular vein oclussion, choroidal neovascularization
• Multifocal electroretinogram before intravitreal bevacizumab and at 1,3, and 6 months after treatment
• Completely studies

Exclusion criteria

Complications

• Tractional Detachment
• Endophthalmitis