Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES)

H. Lee Moffitt Cancer Center and Research Institute

Status: Enrolling

Conditions: Hepatitis C Virus; Colorectal Cancer Screening

Treatments: Behavioral: MATCHES

Study type: Interventional

Funder types: Other

Identifiers

NCT06745895

MCC-23232

Details and patient eligibility

About

This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.

Full description

While this is a multi-level intervention study, only information related to the patient-level intervention is being reported for the purposes ClinicalTrials.gov.

Enrollment: 350 estimated patients

Sex: All

Ages: 45 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants must be receiving care at one of the participating FQHC clinics.
• Participants must be 45-75 years of age.
• Participants must not be up to date with Colorectal Cancer (CRC) screening recommendations such as no colonoscopy in the past 10 years, occult blood test in the past 12 months.
• Participants must never have had Hepatitis C Virus (HCV) antibody screening.
• Participants must be able to read, write, and understand English or Spanish.
• Participants must have no personal history of CRC or current presumptive CRC symptoms such as unresolved rectal bleeding or abdominal pain/bloating.
• Participants must be at average risk for CRC (no hereditary CRC syndromes such as lower gastrointestinal (GI) bleeding, persistent diarrhea, bloating, or lower GI pain, no strong family history of CRC).
• Participants must be asymptomatic for HCV.
• Participants receiving intervention materials must be able and willing to complete surveys and receive the patient level intervention.
• Participants completing qualitative interviews must be willing to complete a remote interview via phone or teleconference software such as ZOOM.
• Participants completing qualitative interviews must be willing to be audio recorded.
• Participants recruited for qualitative interviews only (did not receive MATCHES intervention materials) must have a clinic visit within prior two months.
• All Participants must be able to provide informed consent.

Exclusion criteria

• Participants that do not meet all Inclusion Eligibility requirements will be excluded.

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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350 participants in 1 patient group

Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES)

Experimental group

Description:

The MATCHES intervention includes three patient-level intervention strategies that will be rolled out in two waves. Patient-level strategies are: 1) a combined education booklet with information about CRC/CRC screening and HCV infections/liver cancer/HCV screening in English or Spanish, 2) access to free stool-based CRC screening, and 3) access to free HCV antibody testing.

Treatment:

Behavioral: MATCHES