Multimodal Analysis of the Young Brain on Rhythm Perception: From Premature Neonates to Infants (Exposition)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: EEG; Rhythm; Time Perception; ERP; Discrimination; fNIRS; Premature Neonates

Treatments: Other: NIRS; Other: EEG

Study type: Interventional

Funder types: Other

Identifiers

NCT05417542

PI2021_843_0054

Details and patient eligibility

About

Premature neonates are able to discriminate phonemes and voice from 28wGA at a time the neuronal network establish contact between the environment and the cortical neurones. In the present monocentric study the investigators will analyse the response of the cortical network in premature aged between 28 and 40 wGA in response to auditory stimuli using High Resolution Electroencephalography and High Density Near Infrared Spectroscopy

Enrollment: 200 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Full term neonates between 28 and 40 weeks Gestational Age

Exclusion criteria

• Neonates outside the age range

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 5 patient groups

Exposition I

Experimental group

Description:

preterm neonates between 28 and 30 wGA Exposition to music during the NICU period

Treatment:

Other: NIRS

Other: EEG

Exposition II

Experimental group

Description:

preterm neonates between 32 and 34 wGA Exposition to music during the NICU period

Treatment:

Other: NIRS

Other: EEG

Control I

Active Comparator group

Description:

preterm neonates between 28 and 30 wGA

Treatment:

Other: NIRS

Other: EEG

Control II

Active Comparator group

Description:

preterm neonates between 32 and 34 wGA

Treatment:

Other: NIRS

Other: EEG

Control III

Active Comparator group

Description:

preterm neonates between 36 and 40 wGA

Treatment:

Other: NIRS

Other: EEG