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Multimodal Deep Learning for Lymph Node Metastasis in Thyroid Cancer

S

Sichuan University

Status

Not yet enrolling

Conditions

Papillary Thyroid Carcinoma

Treatments

Other: not intervention

Study type

Observational

Funder types

Other

Identifiers

NCT07299318
2025(2352)

Details and patient eligibility

About

Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy in clinical practice, accounting for approximately 85% of all thyroid malignancies. The occurrence of cervical lymph node metastasis further increases the risk of local tumor recurrence and distant metastasis, thereby reducing patient survival rates. Pathological examinations reveal that approximately 30-80% of PTC patients have lymph node metastasis. Early detection of metastatic lymph nodes and the development of individualized treatment plans are crucial for improving patient prognosis. Currently, the primary method for diagnosing lymph node metastasis is ultrasound-guided fine-needle aspiration, but its accuracy is limited by sample quality and carries a risk of false-negative results. In recent years, deep learning technology has demonstrated significant potential in the field of medical image analysis. Therefore, the investigators aim to develop a deep learning model based on neck ultrasound to more accurately predict lymph node metastasis.

Enrollment

3,200 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Cases aged 18-80 years who underwent thyroid ultrasound examination and postoperative pathological examination of the thyroid.

Cases with a first-time diagnosis of papillary thyroid carcinoma. Cases who underwent lymph node dissection

Exclusion criteria

Cases aged <18 years or >80 years. Cases with poor-quality ultrasound images. Cases with incompletely visualized nodules. Cases with images showing multiple distinct lesions. Cases belonging to special populations. Cases with concurrent other tumors. Cases with a history of thyroid cancer resection

Trial design

3,200 participants in 1 patient group

Papillary thyroid carcinoma group
Treatment:
Other: not intervention

Trial contacts and locations

1

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Central trial contact

Yu Feng; Jianyong Lei

Data sourced from clinicaltrials.gov

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