Multimodal Exercise Program on Parkinson's Disease Patients With Depression

Chang Gung Medical Foundation

Status: Completed

Conditions: Parkinson's Disease

Treatments: Other: exercise group

Study type: Interventional

Funder types: Other

Identifiers

NCT03752346

151223

Details and patient eligibility

About

Depression symptoms are common in Parkinson's Disease, it affects health-related quality of life. The evidence showed that exercise improved depression and HRQOL in PD patients. However, studies rarely considered the appropriate exercise program for PD patients, we want to find the best exercise program for PD patients.

Full description

Objective: Evaluate the effectiveness of a 8-week multimodal exercise program on depression and HRQOL in PD Patients.

Methods: Single-blinded, randomized controlled trial, from March 2016 to January 2017. Ninety-eight patients recruited to 2 groups: exercise group (n = 49) and control group (n = 49). The primary outcomes were depression and HRQOL; the secondary outcomes were activity of daily living, motor ability, fatigue, sleep quality and anxiety. Data collection at baseline, week 4 and 8 after intervention. Intervention were Multimodal Exercise Program, at least three times (30 - 50 minutes per section) a week or 10-15 minutes per section every day to accumulate 150 minutes a week for 8 weeks.

Enrollment: 98 patients

Sex: All

Ages: 40 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• be diagnosed PD in Hoehn and Yahr stage I-II22
• under stable medication treatment at least 3 months
• no disease limiting the patient's ability to perform the exercises

Exclusion criteria

• severe cardiovascular disorders
• neuromusculoskeletal disorder
• cognitive impairment
• recent participation in any physiotherapy or rehabilitation program
• have exercise regularly

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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98 participants in 2 patient groups

control group

No Intervention group

Description:

Control group maintained their regular lifestyle and received the routine care

exercise group

Experimental group

Description:

Participants in the exercise group (EG) were instructed to engage performed exercise at least 3 times per week (30-50 minutes) or 10-15 minutes per section every day to accumulate 150 minutes per week for 8 weeks using disc (DVD) at home. Main exercise was moderate intensity aerobic exercise, an intensity of 55-70% of the heart rate reserve (HR max).

Treatment:

Other: exercise group