Multimodal Monitoring Study in Neuro Critical Care (MultiCU)
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About
During the first week after an acute cerebral injury, neurologic clinical exam is often irrelevant, limited by sedation use or spontaneous consciousness disorders.
Hence, neurological monitoring of brain oxygen consumption, metabolic disorders, electrical activity is used to follow and prevent delayed cerebral injuries. Among those instruments, numerous are often described: intra cranial pressure monitoring, brain tissue oxygen pressure monitoring, scalp electroencephalography, continuous electroencephalography and Near infrared Red Spectroscopy (NIRS).
Even if the value of some of those technologies are well known, many remain part of a research domain. Here we will not only try to study the correlation between different cerebral autoregulation's index described in the scientific literature but also will we try to identify and describe EEG and cardiorespiratory changes during the first week following brain injury. The objective of this study is to investigate the pathophysiology of acute brain injury and explore potent biomarkers of multimodal monitoring during the first week following acute brain injury.
Enrollment
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Inclusion criteria
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- Patients hospitalized in neurologic critical care in Wertheimer Hospital, Bron
- Monitored with the CNS MOBERG® monitoring system
Exclusion criteria
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- Refusal to participate
- Patients under legal protection
Trial design
500 participants in 1 patient group
Trial contacts and locations
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Central trial contact
Dr Baptiste Balança
Data sourced from clinicaltrials.gov
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