Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects (AQ2MF)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Facial Palsy; Eye-tracking; Electromyography

Treatments: Other: Eye-tracking acquisition for pathological subjects; Other: Follow-up visit for pathological subjects; Other: Simultaneous MoCap and EMG acquisition; Other: dental impressions

Study type: Interventional

Funder types: Other

Identifiers

NCT05581680

PI2021_843_0207

Details and patient eligibility

About

The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials. The proposed treatments are based on surgery, physiotherapy and botulinum toxin injections. However, when recovery is incomplete, acceptance is more difficult, with an impacted quality of life. Thanks to Motion Capture and Electromyography, a quantification of the facial mimicry is now possible with a great precision. In addition with the quantification of the facial mimicry, eye-tracking, wich is widely used in the marketing field, but it also finds medical applications including head and neck lesions and facial palsy in particular, will be used to evaluate the visio of the patients on their pathology in function of the movement quantification measured with MoCap and Electromyography. The aim of this research is to measure in a combined way the action potentials by sEMG and the amplitudes of displacement of the markers in motion capture, for movements determined in a population of patients presenting a facial pathology, in order to compare them with reference values obtained in healthy subjects. In a second step, the aim will be to study if there is a link between the way the patient looks at his pathology and the results of his management (treatment, rehabilitation) which will be quantitatively evaluated thanks to MoCap and sEMG.

Enrollment: 720 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects with no known facial pathology (healthy volunteers) OR
• Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated
• Subject with written informed consent
• Subject over 18 years of age
• Subject affiliated to a social security scheme

Exclusion criteria

• Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers
• Subjects with speech disorders making it impossible to pronounce the sounds [o] and [pu]
• Subject unable to provide written informed consent
• Subjects under guardianship, curators or safeguard of justice

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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720 participants in 2 patient groups

patients with facial palsy

Experimental group

Treatment:

Other: Simultaneous MoCap and EMG acquisition

Other: dental impressions

Other: Follow-up visit for pathological subjects

Other: Eye-tracking acquisition for pathological subjects

healthy volunteers

Active Comparator group

Treatment:

Other: Simultaneous MoCap and EMG acquisition

Other: dental impressions