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Multimodal Therapy Impact on Pancreatic Cancer Survival (MMTIPS)

N

National Cheng Kung University

Status

Active, not recruiting

Conditions

Neoadjuvant Chemotherapy
Pancreatectomy
Pancreatic Cancer

Study type

Observational

Funder types

Other

Identifiers

NCT06938906
NCKUH-11405009

Details and patient eligibility

About

The goal of this retrospective cohort study is to analyze change of treatment strategies affect the survival outcomes in patients of pancreatic cancer who received curative-intent treatment. The main question it aims to answer is:

Hypothesis: Change of treatment strategies involving increased utility of neoadjuvant chemotherapy and aggressive surgical approaches of extended pancreatectomy improved the overall and progression free survival in the patients with pancreatic cancer.

Participants received curative treatment for pancreatic cancer.

Full description

This study is to analyze the change of treatment strategies and shift of the paradigm over time in a single center. Researchers plan to see the impact of the evolvement to the survival outcomes in pancreatic cancer.

Enrollment

405 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Pancreatic adenocarcinoma
  • Received curative surgery

Exclusion criteria

  • Other subtypes of pancreatic cancer including acinar cell carcinoma, mucinous carcinoma, undifferentiated carcinoma and intraductal papillary mucinous neoplasm with associated adenocarcinoma
  • Cases with palliative or R2 resection were also excluded from the analysis.

Trial design

405 participants in 2 patient groups

Group A
Description:
The patient of pancreatic cancer, who began to have treatment in the period between 2011 to 2017.
Group B
Description:
The patient of pancreatic cancer, who began to have treatment in the period between 2018 to 2022.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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