Multiparametric Characterization of Orbital Tumors by MRI

Charité University Medicine Berlin

Status: Completed

Conditions: Orbital Tumors

Treatments: Other: MRI

Study type: Observational

Funder types: Other

Identifiers

NCT01884207

MCOT_03_05

Details and patient eligibility

About

Prospective study on patients with orbital tumors of unknown origin. Aim of the study is to differentiate benign from malignant tumors upon MR imaging. Magnetic resonance imaging of the orbit will be performed including standard morphological sequences and advanced sequence techniques. These advanced sequence techniques may allow to differentiate benign from malignant tumors based on their cellularity and vascularity (diffusion and perfusion imaging). These MRI data will be analysed and the level of diffusion and perfusion will be measured and compared to the histological findings. Cut-off values of diffusion and perfusion will be calculated that allow to separate benign from malignant tumors.

Enrollment: 65 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• non-diagnosed orbital tumors

Exclusion criteria

• any metal implants, non-MRI compatible
• age below 18
• pregnancy
• recent surgery
• recent severe medical diseases

Trial design

65 participants in 1 patient group

orbital tumors

Treatment:

Other: MRI