Multiparametric Imaging for Analysis of MVNT (Multinodular and Vacuolating Neuronal Tumor) (MIAM)

Fondation Ophtalmologique Adolphe de Rothschild

Status: Completed

Conditions: Benign Neuronal Desease

Treatments: Device: cerebral MRI

Study type: Observational

Funder types: NETWORK

Identifiers

NCT04103190

ALR_2019_4

Details and patient eligibility

About

Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.

Full description

Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.

However, in order to avoid an invasive surgical procedure to remove the lesion, a certain diagnosis of its benignity is essential. The contribution of advanced techniques in MRI, such as spectroscopy in the characterization of these lesions, has not yet been studied today

Enrollment: 71 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient over 18 years old
• Suspicion of MVNT on an MRI: it is considered that it will be necessary at least the 2 major criteria associated with at least 1 minor criterion to enter the definition of suspicion of MVNT:

Major criteria:

• Multinodular aspect in cluster
• High FLAIR hypersignal / T2

Minor criteria:

• Absence of mass effect

• Hyposignal T1

• Center of the lesion in hypsignal FLAIR or T1 hypersignal

  • Affiliate or beneficiary of a Social Security scheme
  • Having received informed information about the study and consenting to participate in the study

Exclusion criteria

• Patient benefiting from a legal protection measure
• Pregnant or lactating woman
• Contraindication to MRI