Multiparametric MRI for Assessment of Changes of Renal Hemodynamics After Fistula Closure in Kidney Transplant Patients (FISCLO)

University of Zurich (UZH)

Status: Enrolling

Conditions: Kidney Transplantation

Treatments: Diagnostic Test: Echocardiography and MRI

Study type: Observational

Funder types: Other

Identifiers

NCT05015231

2021-00474

Details and patient eligibility

About

Assessment of changes of renal hemodynamics by multiparametric MRI after closure of AVF access.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written informed consent
• Age > 18 years
• Patients wishing to close the fistula and planned for surgical fistula closure
• eGFR CKD EPI ≥ 45 ml/min/1.73m2 at one year post transplantation
• Stable eGFR within the past 6 months
• Controlled blood pressure

Exclusion criteria

• Kidney Transplantation < 12 months before fistula closure
• Proteinuria > 500mg/d
• Presence of donor specific antibodies
• Rejection within the past 6 months
• BK virus replication within the past 3 months
• Cardiac pacemaker, which is not compatible with MRI
• Claustrophobia