Multiphasic Prehab Allo-HSCT

University of Calgary

Status

Not yet enrolling

Conditions

Leukemia

Treatments

Other: Prehabilitation

Study type

Interventional

Funder types

Other

Identifiers

NCT05649371

ACE-HSCT

Details and patient eligibility

About

The purpose of this study is to implement a prehabilitation intervention to enhance recovery for people undergoing allogeneic stem cell transplant for hematologic malignancies. All participants in this study will receive a prehabilation intervention in addition to usual care (no change to their chemotherapy protocols or transplant) and several quality of life and fitness scores will be measured throughout the intervention.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Adult patients, 18 years or older, undergoing an allo-HSCT for acute leukemia.
Approval to engage in exercise as per screening by the CSEP or ACSM certified CEP and/or clinician
Ability to provide written informed consent and understand study information.

Exclusion criteria

Less than 18 years old
Diagnosed with acute leukemia but not undergoing work-up for allo-HSCT
Unable to read/communicate in English (i.e., unable to complete experimental procedures such as patient-reported outcomes).
Neurological or musculoskeletal comorbidity inhibiting exercise.
Diagnosed psychotic, addictive, or major cognitive disorders.
Severe coronary artery disease (Canadian Cardiovascular Society class III or greater).
Significant congestive heart failure (New York Heart Association class III or greater).
Severe thrombocytopenia (platelets <10) - ok if transfused platelets prior to exercise.