Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology
Status
Conditions
Treatments
Details and patient eligibility
About
We use multiphoton laser scanning microscopy to observe cutaneous anatomy and pathology. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy.
Full description
For skin diseases, the most convincing method for diagnosis to date is surgical biopsy. However, a skin biopsy is an invasive procedure which carries the risk of tissue damage, wound infection and scar formation. To solve the inconvenience from surgical biopsy, multiphoton laser scanning microscopy is a developing, non-invasive method for observing the cutaneous anatomy and pathology. Multiphoton laser scanning microscopy is good in tissue penetration and resolution with less tissue damage. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy. A good correlation in multiphoton image may serve as optical biopsy for cutaneous pathology and spare the invasive procedure of skin biopsy.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Patients receiving cosmetic surgeries such as removal of moles
Exclusion criteria
- No special exclusion criteria
Trial contacts and locations
Loading...
Central trial contact
Shiou-Hwa Jee, MD PhD
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal