Multiple Myeloma Yoga Pilot Study

University of Arizona

Status: Completed

Conditions: Multiple Myeloma

Treatments: Other: Immediate yoga intervention; Other: Delayed yoga intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT06061302

STUDY00003083

Details and patient eligibility

About

The purpose of this study is to evaluate the feasibility of implementing a weekly yoga intervention in patients with multiple myeloma on active therapy. This study aims to analyze the impact of yoga intervention on physical symptoms (e.g. pain, fatigue, sleep), psychological symptoms (e.g. anxiety, depression), and overall health-related quality of life (HRQOL) in multiple myeloma patients on active treatment.

Enrollment: 31 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any adult of age 18 and above
• Able to understand basic English
• Able to provide informed consent
• Diagnosis of multiple myeloma on active treatment as determined by investigators
• Good performance status as defined by European Cooperative Oncology Group score 0-1
• Able to utilize computer/laptop and smart phone
• Able and willing to travel to the yoga studio for weekly sessions
• Able to utilized a wearable device, such as Apple Watch or Fitbit (optional)

Exclusion criteria

• Poor performance status with European Cooperative Oncology Group score 2-4
• Actively participating in another clinical trial
• Poorly controlled mental health symptoms as determined by treating physician
• Reported fall or syncope in the last 2 months prior to enrollment
• Concurrent diagnosis of amyloidosis or other cancer requiring active treatment

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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31 participants in 2 patient groups

Immediate yoga group

Experimental group

Description:

20 participants randomized to immediate yoga intervention group will participate together in a weekly 40-minute guided mindful yoga intervention for a total of 12 consecutive weeks. After each session, participants will be asked to complete the Edmonton Symptom Assessment System (ESAS-r) through MyDataHelps app. At the end of each session, participants will be asked additional questions via MyDataHelps such as completion of yoga session on-site or remotely, the length of time they participated in the session, any additional yoga sessions during the past week, and comments regarding the session/intervention. These participants will also complete health-related quality of life (HRQOL) assessment (EORTC QLQ-C30) at baseline, 6 weeks, and 12 weeks during active yoga intervention.

Treatment:

Other: Immediate yoga intervention

Waitlist yoga group (delayed yoga intervention group)

Active Comparator group

Description:

20 participants randomized to this group will start the yoga intervention at week 13 and participate in 12 consecutive weeks of weekly 40 minute guided mindful yoga. Participants in this group will complete ESAS-r every 3 weeks and EORTC QLQ-C30 every 6 weeks for the first 12 weeks. These participants will also complete HRQOL assessment (EORTC QLQ-C30) at baseline, 6 weeks, and 12 weeks during active yoga intervention, weeks 13-24.

Treatment:

Other: Delayed yoga intervention