Multiple Sclerosis and Respiratory and Functional Capacity

Nigde Omer Halisdemir University

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Expanded Disability Status Scale, pulmonary function test, International Physical Activity Questionnaire - Short Form, 6 minute walk test

Study type: Observational

Funder types: Other

Identifiers

NCT05697523

60116787-020/92286

Details and patient eligibility

About

It is known that respiratory functions, physical activities and functional capacities of Multiple Sclerosis (MS) patients decrease with the progression of the disease. However, there is not enough information about the severity of the effects of these parameters in mild Relapsing-Remitting Multiple Sclerosis (RRMS) patients. Our aim in this study is to compare the respiratory functions, physical activities and functional capacities of mild RRMS patients with healthy controls and to examine the relationship between them.

Full description

It is known that respiratory functions, physical activities and functional capacities of Multiple Sclerosis (MS) patients decrease with the progression of the disease. However, there is not enough information about the severity of the effects of these parameters in mild Relapsing-Remitting Multiple Sclerosis (RRMS) patients. Our aim in this study is to compare the respiratory functions, physical activities and functional capacities of mild RRMS patients with healthy controls and to examine the relationship between them.

Forty individuals diagnosed with RRMS between the ages of 18-60 and 40 healthy individuals with similar demographic characteristics were included in the study.

Enrollment: 80 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Patient group - Inclusion Criteria:

• Having a definitive diagnosis of RRMS according to the 2017 McDonald criteria
• Being between the ages of 18-60.
• To be willing to participate in the study.
• EDSS score between 0-3.

Healthy group - Inclusion Criteria:

• Being between the ages of 18-60.
• To be willing to participate in the study.

Patient group - Exclusion Criteria:

• Have other neurological, orthopedic and systemic problems
• Having a relapse 30 days before or during the study
• Changes in medication use in the past 30 days

Healthy group - Exclusion Criteria:

• Have neurological, orthopedic and systemic problems

Trial design

80 participants in 2 patient groups

Patient group

Description:

people with mild RRMS

Treatment:

Other: Expanded Disability Status Scale, pulmonary function test, International Physical Activity Questionnaire - Short Form, 6 minute walk test

Healthy group

Description:

healthy people

Treatment:

Other: Expanded Disability Status Scale, pulmonary function test, International Physical Activity Questionnaire - Short Form, 6 minute walk test