Multiple System Atrophy Multidisciplinary Clinic

The University of Texas System (UT)

Status: Enrolling

Conditions: Multiple System Atrophy (MSA)

Study type: Observational

Funder types: Other

Identifiers

NCT03811808

STU 082015-008

Details and patient eligibility

About

This is a prospective cohort study to examine the disease burden of multiple system atrophy and the impact of multidisciplinary care on quality of life and caregiver burden. Data will be collected through valid rating scales completed by patients and caregivers at home or in the MSA clinic.

Full description

Study Procedures:

Participants and caregivers will attend a multidisciplinary MSA clinic one day every four months. In addition to the standard of care, they will be asked to complete both online and paper questionnaires, including the following:

• UMSARS (Unified MSA Rating Scale)
• MSA QOL
• CES-D
• OHQ
• Compass-31
• BIC
• UPDRS
• SARA
• MDS Scale
• CGI
• MoCA

Participants will be part of the study as long as they are a patient of the MSA clinic, and will be contacted for follow-up information up to five years.

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject must be a patient in the UT Southwestern MSA clinic and be able to attend the multidisciplinary clinic every 4 months
• Patients with possible or probable MSA based on established criteria
• Subjects must be 18 years or older

Exclusion criteria

• Patients that are unable to give consent
• Minor patients (younger than age 18)
• Non-English speaking patients
• Subjects that are diagnosed with dementia

Trial design

200 participants in 1 patient group

MSA patients

Description:

patients diagnosed with possible or probable multiple system atrophy