MultiPoint Pacing Programming Guided by Noninvasive Hemodynamics

Abbott

Status

Completed

Conditions

Heart Failure

Treatments

Procedure: Hemodynamic measurements for CRT device programming

Device: CRT with MultiPoint Pacing

Study type

Interventional

Funder types

Industry

Identifiers

NCT02064751

CRD_704

Details and patient eligibility

About

The purpose of this study is to evaluate noninvasive hemodynamics with MultiPoint™ Pacing (MPP) and biventricular (BiV) pacing under various vector combinations and paced delays in patients receiving cardiac resynchronization therapy (CRT).

Enrollment

40 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Be scheduled to undergo de novo implant of a St. Jude Medical CRT-D system
Be in NYHA II or III functional class with approved standard indication by ESC/EHRA Guidelines
Have the ability to provide informed consent for study participation and be willing and able to comply with the Clinical Investigation Plan (CIP) described evaluations and follow-up schedule

Exclusion criteria

Have persistent or permanent atrial fibrillation
Have a recent myocardial infarction within 40 days prior to enrollment
Have undergone cardiac surgery or coronary revascularization procedure within 3 months prior to enrollment or be scheduled for such procedures in the following 12 months
Have had a recent Cerebrovascular Accident (CVA) or Transient Ischemic Attack (TIA) within 3 months prior to enrollment
Have had intravenous inotropic support in the last 30 days
Be scheduled or considered for heart transplantation over the next 12 months
Be less than 18 years of age
Be pregnant or plan to become pregnant over the next 12 months