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Multivariate Analysis and Risk Factors Were Used to Predict the Short-term Postoperative Pain of Degenerative Lumbar Spine

H

Hao Liu

Status

Completed

Conditions

Lumbar Degenerative Disease
Lumbar Disc Herniation
Sarcopenia

Treatments

Other: Magnetic Resonance Imaging with Contrast

Study type

Observational

Funder types

Other

Identifiers

NCT06628583
(2024) Lun Yan Grant No. 518

Details and patient eligibility

About

The objective of this retrospective clinical study wasto study the risk factors for short-term low back and leg pain after PLIF in patients with lumbar Degenerative disease, and to establish a risk prediction model for short-term low back and leg pain after PLIF based on relevant risk factors.

Enrollment

936 patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. confirmed diagnosis of lumbar degenerative disease (spinal stenosis, disc herniation with lumbar instability, and lumbar spondylolisthesis), with no significant symptomatic relief after conservative treatment for more than 3 months, and in need of surgical intervention;
  2. lumbar spinal fusion surgical treatment with PLIF;
  3. grouping based on the presence or absence of a lumbar or limb pain with VAS ≥3 at the 3th month postoperative follow-up;
  4. observational indicators including individual factors, surgical factors, spine-pelvis sagittal balance parameters, and paravertebral muscle parameters.

Exclusion criteria

(1) those with a history of lumbar spine trauma, inflammation, tumor, or surgery; (2) those with congenital or acquired severe lumbar vertebral deformity; (3) those with severe neurological dysfunction; (4) those with incomplete baseline and follow-up data.

Trial design

936 participants in 2 patient groups

Rehabilitation Group
Description:
mild/non pain group with VAS\<3 at 3th months after PLIF.N=501
Treatment:
Other: Magnetic Resonance Imaging with Contrast
Recurrent pain group
Description:
Recurrent pain group: recurrent pain group with VAS≥3 at 3th months after PLIF.N=435
Treatment:
Other: Magnetic Resonance Imaging with Contrast

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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