Multivisceral Radical Resection for Surgical T4b Colorectal Cancer: Propensity Score-matched Study Comparing the the Laparoscopic and Open Approaches (C-PelvEx-01)
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This study attempts to compare safety and long-term oncological outcomes between laparoscopic surgery and open surgery in the treatment of clinical T4b Colorectal cancer.
Full description
Laparoscopic surgery is controversial for patients with T4b colorectal cancer who require multivisceral resection. With the expansion of the indications for laparoscopic surgery in recent years, surgeons try to perform laparoscopic multivisceral resection for the treatment of clinical T4b colorectal cancer. In this study, investigators attempted to compare safety and long-term oncological outcomes between laparoscopic surgery and open surgery in the treatment of clinical T4b colorectal cancer.
This study was a multicenter retrospective cohort study based on a multicenter database which contained hospitalization. According to the operation method, the patients were divided into laparoscopic multivisceral resection group(patients who underwent laparoscopic surgery or conversion to open surgery) and open multivisceral resection group(patients who underwent open surgery directly). The short-term and long-term result was compared between groups.
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Inclusion criteria
- The patient was pathologically diagnosed as colorectal adenocarcinoma by endoscopic biopsy before operation.
- All patients were considered to have tumors invading adjacent organs after preoperative radiographic evaluation.
- All patients were recommended to undergo radical surgery after preoperative multidisciplinary consultation.
Exclusion criteria
Patients with distant metastasis or recurrent colorectal cancer were excluded.
Trial design
638 participants in 2 patient groups
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Data sourced from clinicaltrials.gov
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