Cluster Analysis to Identify Metabolic Syndrome Components and Physical Fitness in Patients With Metabolic Syndrome

Istanbul Galata University

Status: Completed

Conditions: Metabolic Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT05569642

IstanbulGalataUni

Details and patient eligibility

About

The components of MetS (abdominal obesity, high blood pressure, high serum glucose, high triglyceride level and low HDL-C) differ according to demographic characteristics such as age, gender and comorbidities. Low physical activity level, genetic makeup, nutritional disorders, decreased muscle strength and low cardiorespiratory fitness can be counted among the risk factors associated with MetS. In our study, it was aimed to examine the relationship between the components of the MetS and muscle strength, physical activity, functional capacity and quality of life. Our secondary aim is to investigate the independent effects of different components of MetS on each parameter.

Full description

The participants' sociodemographic characteristics such as age, height, weight, body mass index, waist circumference, marital status and education level, and anthropometric measurements, body fat percentage distributions, fasting blood glucose, HbA1c and lipid profiles will be recorded from previous analysis reports. Lower extremity quadriceps muscle strength Hand-held dynamometer, grip strength hand dynamometer, physical activity level International Physical Activity Questionnaire-Short Form-IPAQ-SF, number of steps pedometer, functional capacity 6 minute walking test and quality of life will be evaluated with the European Quality of Life Scale-5 Dimension.

Enrollment: 112 patients

Sex: All

Ages: 40 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• To be diagnosed with MetS by an Internal Medicine Specialist according to NCEP-ATP III criteria
• Finding abdominal obesity component according to TURDEP-II criteria
• Being between the ages of 40-65
• To be able to read and write Turkish
• Having signed the informed consent form

Exclusion criteria

• Lack of cooperation
• Those with severe peripheral or central neurological disorders
• Patients with uncontrolled hypertension and uncontrolled arrhythmia
• Pregnant or breastfeeding patients
• Those with diabetic ulcer or neuropathy
• Chronic kidney failure (eGFR<30 ml/min)
• Chronic liver disease (ALT/AST<3X Normal upper limit)
• Those with serious respiratory system disease
• Patients with cardiac pacemaker
• History of previous stroke or myocardial infarction
• Presence of lower and upper extremity orthopedic problems that may prevent the application of clinical tests