Muscle Inflammation and Fat Infiltration in Patients Affected by FSHD

Rigshospitalet

Status: Unknown

Conditions: Facioscapulohumeral Muscular Dystrophy 1a

Treatments: Other: No intervention, observational

Study type: Observational

Funder types: Other

Identifiers

NCT02541292

H-15009760

Details and patient eligibility

About

Facioscapulohumeral muscular dystrophy (FSHD) is the second most common muscular dystrophy with approximately 500 patients in Denmark. It is characterized by weakness and wasting of the facial muscles, the muscles in the shoulder region and of the legs.

The primary aim of this study is to investigate possible links and order between inflammation and fat infiltration in the muscles in patients with FSHD.

Approximately 15 patients with FSHD will be recruited for repeated MRI-scans during a year where the inflammation and fat infiltration in the muscles can be quantified.

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed FSHD

Exclusion criteria

• All contraindications for undergoing an MRI scan

Trial design

10 participants in 1 patient group

Patient group

Description:

Patients over 18 years old with confirmed FSHD (facioscapulohumeral muscular dystrophy).

Treatment:

Other: No intervention, observational