Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis

The Hong Kong Polytechnic University

Status

Completed

Conditions

Osteoarthritis, Knee

Treatments

Other: Exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT03628508

HSEARS20170406003

Details and patient eligibility

About

Knee osteoarthritis (KOA) is a common chronic painful musculoskeletal condition among older adults. It poses great challenge to the health care system due to its inability to be cured. Understanding factors associated with disease progression in KOA should assist the development of novel prevention/rehabilitation strategies. This study investigate factors including muscle properties, lower limb alignment and joint loading in patients with knee osteoarthritis before and after a six-week exercise program.

Enrollment

40 patients

Sex

All

Ages

50 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age between 50-80
having radiographic tibiofemoral joint OA in the medial compartment defined as Kellgren and Lawrence grade = 2 to 3
having medial knee pain on most days of the month
having a minimum average pain score of 2 on an 11-point numerical rating scale in the past week while walking

Exclusion criteria

having lateral tibiofemoral compartment osteophytes greater than the medial side.
having undergone intra-articular corticosteroid injection or knee surgery to either knee within the past 3 months
having a systemic arthritic condition (e.g., rheumatoid arthritis)
having a knee joint replacement or high tibial osteotomy in the past
having any other muscular, joint or neurological condition influencing lower limb function
unable to walk unaided
having low back, hip, ankle or foot pain > 3 on numerical rating scale
having a body mass index (BMI) >36 kg/ m2