Muscle Relaxants on Efficacy of LMA Insertion (LMA_MR)

Daegu Catholic University Medical Center

Status: Completed

Conditions: Anesthesia Intubation Complication

Treatments: Drug: rocuronium; Drug: saline

Study type: Interventional

Funder types: Other

Identifiers

NCT03487003

DCMC#3

Details and patient eligibility

About

The use of laryngeal mask airway (LMA) is increasing in pediatric anesthesia because it provides lesser direct mechanical stimulation of the airway due to being placed above the larynx. However, LMA insertion can be more difficult in children than in adults due to their unique characteristics of pediatric airway. Neuromuscular blocking agents, so-called, muscle relaxants have long been used to facilitate insertion of airway devices. But there are pros and cons for the efficacy of muscle relaxants in LMA insertion, and most studies were investigated in adults.

Enrollment: 128 patients

Sex: All

Ages: 2 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged between 2 and 7 years of American Society of Anesthesiologists physical status (ASA PS) I or II who are planned to receive ophthalmic surgery under general anesthesia

Exclusion criteria

• Refusal of consent
• Present URI or other respiratory symptoms
• Oro or facial anomaly
• Poor dental condition
• who cannot open their mouth or limited mouth opening
• when the tracheal intubation is definitely needed

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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128 participants in 2 patient groups

MR group

Active Comparator group

Description:

When the patients asleep, 0.3 mg/kg rocuronium is administered.

Treatment:

Drug: rocuronium

NMR group

Experimental group

Description:

When the patients asleep, 0.3 mg/kg saline is administered.

Treatment:

Drug: saline