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Muscle Strength Evaluations in Ankylosing Spondylitis

B

Bezmialem Vakif University

Status

Completed

Conditions

Ankylosing Spondylitis

Treatments

Other: Truncal flexion-extension muscle power
Other: Cervical lateral flexion muscle powers
Other: Cervical flexion muscle power
Other: The Health assessment questionnaire (HAQ)
Other: Shoulder internal rotation muscle power
Other: Bath Ankylosing Spondylitis Functional Index (BASFI)
Other: Hip abduction muscle power
Other: Cervical extension muscle power
Other: Hip extension muscle power
Other: Hip external rotation muscle power
Other: Hip flexion muscle power
Other: Hip internal rotation muscle power
Other: Shoulder flexion muscle power
Other: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
Other: Truncal extension muscle power
Other: Shoulder extension muscle power
Other: Bath Ankylosing Spondylitis Metrology Index (BASMI)
Other: Shoulder external rotation muscle power
Other: Shoulder abduction muscle power

Study type

Observational

Funder types

Other

Identifiers

NCT04435860
2019-08/115

Details and patient eligibility

About

This study evaluates how the trunk and proximal girdle muscles are affected in male patients with ankylosing spondylitis, compared to healthy controls.

Full description

Ankylosing spondylitis is a chronic, inflammatory rheumatic disease with an unclear etiology which causes back pain and affects the functionality of axial skeleton. Besides the effect upon axial skeleton, the disease also affects the peripheral joints. In most patients, tenuous affection of peripheral joints occurs however, in some others the disease causes impaired spinal mobility and articular instability. This causes proximal girdle muscles and trunk muscles of the patients to be exposed to excessively stress and in conclusion deformities develop. Maximum force generated by a muscle or muscle group directly effects the physical ability of an individual, and manual muscle dynamometers are used to directly evaluate the muscle strength. In this manner the investigators aim to evaluate trunk and proximal girdle muscles' powers in male patients with ankylosing spondylitis and analyze the correlation between muscle powers, and functionality and disease activity.

Read more

Enrollment

100 patients

Sex

Male

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. Having a diagnosis of ankylosing spondylitis according to Modified NewYork criteria
  2. Being male
  3. Aged ≥18

Exclusion criteria

  1. Severe cardiac or pulmonary or renal disease
  2. Accompanying fibromyalgia
  3. Severe psychiatric disorder
  4. Other disease limiting spinal, shoulder or hip range of motion
  5. Myopathy, neuropathy or radiculopathy that may cause muscle weakness
  6. Using high dose steroids
  7. Endocrinological disorders
  8. Malignancy
  9. Pregnancy

Trial design

100 participants in 2 patient groups

Ankylosing Spondylitis
Description:
Patients with ankylosing spondylitis meeting the inclusion and exclusion criteria
Treatment:
Other: Truncal flexion-extension muscle power
Other: Shoulder flexion muscle power
Other: Hip flexion muscle power
Other: Bath Ankylosing Spondylitis Functional Index (BASFI)
Other: Shoulder external rotation muscle power
Other: Cervical lateral flexion muscle powers
Other: Shoulder internal rotation muscle power
Other: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
Other: Shoulder abduction muscle power
Other: Cervical flexion muscle power
Other: Truncal extension muscle power
Other: Shoulder extension muscle power
Other: Bath Ankylosing Spondylitis Metrology Index (BASMI)
Other: Hip internal rotation muscle power
Other: Cervical extension muscle power
Other: The Health assessment questionnaire (HAQ)
Other: Hip extension muscle power
Other: Hip abduction muscle power
Other: Hip external rotation muscle power
Healthy Controls
Description:
Healthy individuals meeting the exclusion criteria
Treatment:
Other: Truncal flexion-extension muscle power
Other: Shoulder flexion muscle power
Other: Hip flexion muscle power
Other: Shoulder external rotation muscle power
Other: Cervical lateral flexion muscle powers
Other: Shoulder internal rotation muscle power
Other: Shoulder abduction muscle power
Other: Cervical flexion muscle power
Other: Truncal extension muscle power
Other: Shoulder extension muscle power
Other: Hip internal rotation muscle power
Other: Cervical extension muscle power
Other: Hip extension muscle power
Other: Hip abduction muscle power
Other: Hip external rotation muscle power

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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