Musculoskeletal Health in Adult Haematological Cancer Survivors (SKETCh)

The Christie NHS Foundation Trust

Status: Enrolling

Conditions: Musculoskeletal Complication; Cancer Survivors; Lymphoma; Leukemia

Treatments: Other: Not an intervention study

Study type: Observational

Funder types: Other

Identifiers

NCT05865678

CFTsp167

Details and patient eligibility

About

Haematological cancer treatment often includes use of high dose glucocorticoids (steroids), chemotherapy and radiotherapy and current evidence suggests that these patients may have lower bone mineral density after treatment when compared to the general population which can predispose them to increased risk of fragility fractures. Evidence of the impact of these musculoskeletal burden to patients (e.g. quality of life) are not available.

This study aims to describe musculoskeletal complications experienced by long-term haematological cancer survivors and examine the impact of the burden from the patient perspective. The study will be conducted in 2 parts; a questionnaire study and an interview study to help understand the extent of musculoskeletal problems experienced by this group of patients and the impact of this on quality of life.

Enrollment: 650 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Questionnaire study

Inclusion Criteria:

1. Age 18 or above at diagnosis of haematological cancer
2. Diagnosis of haematological cancers: lymphoma or leukaemia
3. Cancer survivors as recorded in the local database of lymphoma and haematopoietic stem cell transplant database
4. Able to give written informed consent
5. Able to read and understand English

Exclusion Criteria:

1.Currently receiving any active cancer treatment

Interview study

Inclusion Criteria:

1. Age 18 or above at diagnosis of haematological cancer
2. Diagnosis of haematological cancers: lymphoma or leukaemia
3. Cancer survivors as recorded in the local database of lymphoma and haematopoietic stem cell transplant database
4. Able to give written or verbal informed consent
5. Able to read and understand English

Exclusion Criteria:

1 .Currently receiving any active cancer treatment

Trial design

650 participants in 32 patient groups

5-10 years post cancer treatment; male; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; male; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; male; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; male; age at diagnosis 70+

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; female; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; female; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; female; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

5-10 years post cancer treatment; female; age at diagnosis 70+

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; male; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; male; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; male; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; male; age at diagnosis 70+

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; female; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; female; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; female; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

11-20 years post cancer treatment; female; age at diagnosis 70+

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; male; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; male; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; male; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; male; age at diagnosis 70+

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; female; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; female; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; female; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

21-30 years post cancer treatment; female; age at diagnosis 70+

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; male; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; male; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; male; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; male; age at diagnosis 70+

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; female; age at diagnosis 18-30

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; female; age at diagnosis 31-50

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; female; age at diagnosis 51-70

Treatment:

Other: Not an intervention study

30 years + post cancer treatment; female; age at diagnosis 70+

Treatment:

Other: Not an intervention study