Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)

Johns Hopkins Medicine

Status: Not yet enrolling

Conditions: Feasibility Studies

Treatments: Other: Music intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT07375992

J2556

IRB00493841 (Other Identifier)

Details and patient eligibility

About

The Brain Cancer Program, in partnership with the Center for Music and Medicine at Johns Hopkins, will study whether music therapy is feasible in newly diagnosed GBM patients undergoing standard care.

Full description

Virtually via Zoom, all participants will meet with Music Therapists to create playlists and learn how to complete surveys measuring quality of life.

Participants will be randomly assigned, half to each arm. Arm A will interact with Music Therapists and listen to music twice a week, then independently fill out quality of life questionnaires.

Arm B will listen to music independently twice a week, then independently fill out quality of life questionnaires.

Enrollment: 35 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Glioblastoma
• Cognitive capacity to respond to surveys
• Access to computer and web access
• Ability to attend virtual music therapy sessions
• Audibly process music
• Proficient in English

Exclusion criteria

• Not planning to undergo standard of care radiation therapy and concurrent and adjuvant temozolomide.
• A life expectancy of less than 6 months.
• Concurrent use of any other standard or investigational agents (excepting tumor treating fields).
• Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection or psychiatric illness/social situations that would limit adherence with study requirements.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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35 participants in 2 patient groups

Arm A- with Music Therapists

Experimental group

Description:

Arm A of the study will involve individuals who are assigned to receive twice weekly music therapy sessions with a Music Therapist. These live sessions will be conducted virtually via a Johns Hopkins Compliance virtual platform (e.g., Zoom) each session will last 30 minutes. Participants will complete a total of 16 music therapy sessions, and the frequency is 2 sessions per week for 8 weeks. Participants will complete surveys measuring quality of life once each week.

Treatment:

Other: Music intervention

Arm B- without Music Therapists

Experimental group

Description:

Arm B of the study participants will meet with a music therapist to create a curated playlist. The participant will then listen independently to music therapy sessions twice a week for thirty minutes. Participants will complete a total of 16 music therapy sessions, and the frequency is 2 sessions per week for 8 weeks. Participants will complete surveys measuring quality of life once each week.

Treatment:

Other: Music intervention