Music Therapy on Nausea and Pain for Autologous Stem Cell

Case Comprehensive Cancer Center (Case CCC)

Status: Completed

Conditions: Hodgkin Lymphoma; Multiple Myeloma; Non-Hodgkin Lymphoma

Treatments: Other: Music Therapy; Other: No music therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01487031

CASE11Z10

Details and patient eligibility

About

Autologous stem cell transplant (ASCT) is an important therapy for patients with multiple myeloma, non-Hodgkin's lymphoma, and Hodgkin's lymphoma. It has been shown to improve progression free survival and overall survival. However, it is a challenging treatment process both physically and psychologically. It is a procedure with many side effects that can be uncomfortable, painful, and at times, difficult to endure. Complementary therapies, such as music therapy, have potential to be an important adjunct in palliation of symptoms in patients undergoing chemotherapy.

Full description

Patients randomized to receive music therapy will receive 2 sessions of live music therapy, at least 48 hours apart, from a Music Therapist-Board Certified (MT-BC, certified through the Certification Board for Music Therapists) in their room. This will occur between days -1 and +5, with the first music therapy session being as close to day +1 as possible and the second session being at least 48 hours later (but no more than 96 hours later).

Those patients randomized to standard therapy (no music therapy) are allowed to listen to music; however they will not receive interactive music therapy from a certified therapist. Following day +7, music therapy will be offered to all patients who are interested in participating.

No narcotic or anti-emetic therapy will be administered for at least 2 hours prior to music therapy sessions or to assessments. Patients will rate nausea and pain at the beginning and end of the first music therapy session on a validated visual analog scale.12-14 The scale will be 10cm with the least nausea or pain at point 0 and the greatest nausea or pain at point 10. Patients will be asked to rate their nausea and pain on day +5 and day +7.

Enrollment: 108 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Be older than 18 years of age
• Have a diagnosis of multiple myeloma, non-Hodgkin, or Hodgkin lymphoma
• Be undergoing ASCT (Autologous Stem Cell Transplantation)

Exclusion criteria

• Have had previous ASCT
• Have a diagnosis of leukemia
• History of prior music therapy

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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108 participants in 2 patient groups

Music Therapy

Experimental group

Description:

Patients randomized to receive music therapy will receive 2 sessions of live music therapy, at least 48 hours apart, from a Music Therapist-Board Certified (MT-BC, certified through the Certification Board for Music Therapists) in their room.

Treatment:

Other: Music Therapy

No music therapy

Active Comparator group

Description:

Those patients randomized to standard therapy (no music therapy) are allowed to listen to music; however they will not receive interactive music therapy from a certified therapist.

Treatment:

Other: No music therapy