Mycoprotein and Muscle Protein Synthetic Response (PIMP)

University of Exeter

Status: Completed

Conditions: Anabolic Response to Mycoprotein and Micronutrient Ingeston

Treatments: Dietary Supplement: Mycoprotein ingestion

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT04084652

190206/B/07UOE

Details and patient eligibility

About

Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues. Accordingly, there is a need to develop an understanding of the utility of more sustainable non-animal derived dietary proteins to support our nutrition. Mycoprotein, produced by Quorn Foods™, has recently been shown to stimulate a greater anabolic response within skeletal muscle compared with milk protein, suggesting its utility within sports nutrition. However, it is unclear what accounted for the greater anabolic response of mycoprotein. One explanation could be the non-protein nutrients contained within mycoprotein (e.g. fibre, carbohydrate, fat or micronutrients).

Therefore, the present study will compare the muscle anabolic response between mycoprotein (MYC) as a whole food and the protein isolated from mycoprotein (PIM).

Enrollment: 24 patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI between 18 and 30.
• Resistance trained

Exclusion criteria

• Any metabolic impairments.
• Cardio/pulmonary diseases.
• Chronic use of over the counter pharmaceuticals
• A personal or family history of epilepsy, seizures or schizophrenia.
• Allergic to mycoprotein/Quorn/edible fungi/environmental mould products.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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24 participants in 2 patient groups

Mycoprotein

Experimental group

Description:

Mycoprotein in its full food matrix

Treatment:

Dietary Supplement: Mycoprotein ingestion

Protein Isolated from Mycoprotein

Experimental group

Description:

Protein from mycoprotein isolated from the food matrix

Treatment:

Dietary Supplement: Mycoprotein ingestion