Myeloid-derived Suppressor Cells in Sepsis

Chung Fu-Tsai

Status: Unknown

Conditions: Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT03540797

IRB103-6424B

Details and patient eligibility

About

This study is designed for septic patients, to isolate MDSCs and the correlation of prognosis of sepsis. The purpose of this study hopes to explore the phenomenon and possible mechanisms of MDSCs in patients with severe sepsis.

Enrollment: 125 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients must have known origin of infection .
• Systemic inflammatory response syndrome.

Exclusion criteria

• age less than 18 years
• pregnancy
• known anaphylactoid reaction to colloid fluids
• a life expectancy less than 24 hours,
• inability to provide informed, written consent
• Patients receiving nephrotoxic drugs,
• admitted to the hospital following a surgical procedure,
• sepsis more than 72 hours when screening .

Trial design

125 participants in 1 patient group

Intensive care unit (ICU) patients with sepsis