Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity

Muhammad Aamir Latif

Status

Completed

Conditions

Polycystic Ovarian Syndrome

Treatments

Drug: Metformin

Drug: Myo-inositol

Study type

Interventional

Funder types

Other

Identifiers

NCT07387679

Dr-Ayesha-BVH

Details and patient eligibility

About

There are considerable gaps in the comparative effectiveness and tolerability of myo-inositol and metformin for treating obesity in patients with polycystic ovarian syndrome (PCOS). The current study aimed to give insights comparing myo-inositol versus metformin for treating obesity in patients with PCOS.

Full description

A review of the literature reveals inconsistent outcomes of myo-inositol vs metformin in the treatment of obesity and metabolic disorders in patients with PCOS, with comparable results and myo-inositol frequently demonstrating superior tolerability and reduced gastrointestinal side effects relative to metformin. When treating obesity in women with PCOS, practicing gynecologists would be able to select more appropriate medications by gathering data from local contexts. It will lessen psychological consequences associated with obesity, such as discrimination, stigma, low self-esteem, and poor quality of life.

Enrollment

60 patients

Sex

Female

Ages

18 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Females aged 18-45 years
Diagnosed case of PCOS for more than 6 months of duration

Exclusion criteria

Women with hyperprolactinemia or hypothyroidism (on history & medical record review)
Adrenal hyperplasia or Cushing's syndrome (on history & medical record review)