Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

Mayo Clinic

Status: Completed

Conditions: Healthy Adults

Treatments: Diagnostic Test: Real-Time Myocardial Echocardiography (RTMPE); Diagnostic Test: Magnetic resonance image (MRI)

Study type: Interventional

Funder types: Other

Identifiers

NCT04724304

20-000936

Details and patient eligibility

About

This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.

Enrollment: 115 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years.
• Available for testing performed in Rochester, MN.
• Willing to undergo both an echocardiogram with RTMPE and CMR.
• Study subject providing consent.

Exclusion criteria

• Adults < 18 years.
• BMI <30 kg/m^2.
• Hypertension.
• Diabetes Mellitus.
• Stroke.
• Cardiomyopathy or structural heart disease.
• Known coronary artery disease or history of myocardial infarction.
• Contraindication to echo enhancement agent or gadolinium administration such as an allergy.
• Renal GFR < 50 mL/mL.
• Females who are pregnant.
• Subject unwilling to consent.

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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115 participants in 1 patient group

Healthy adults

Experimental group

Description:

Healthy adults will have blood flow to the heart evaluated using s Real-Time Myocardial Echocardiography (RTMPE) and magnetic resonance image (MRI) to the heart.

Treatment:

Diagnostic Test: Real-Time Myocardial Echocardiography (RTMPE)

Diagnostic Test: Magnetic resonance image (MRI)