Myocardial Bridging in Obstructive Hypertrophic Cardiomyopathy (MB in oHCM)

Chinese Academy of Medical Sciences, Fuwai Hospital

Status: Completed

Conditions: Myocardial Bridging; Atrial Fibrillation (AF); Obstructive Hypertrophic Cardiomyopathy

Treatments: Procedure: Coronary artery bypass grafting or unroofing

Study type: Observational

Funder types: Other

Identifiers

NCT06598995

2022-1892

2022-GSP-GG-29 (Other Grant/Funding Number)

Details and patient eligibility

About

This study investigated the impact of myocardial bridging (MB) and its characteristics on preoperative atrial fibrillation and survival in patients with obstructive hypertrophic cardiomyopathy (oHCM). We recruited 968 consecutive patients with oHCM who underwent myectomy at our institution between January 2015 and December 2019, including 144 patients with MB and 824 patients without MB. All patients received angiography before surgery. The diagnosis of preoperative atrial fibrillation was based on 12-lead electrocardiography, 24-hour Holter electrocardiography, or in-hospital electrocardiogram monitoring, which was extracted from patients' medical records. Surgical details and follow-up data were also collected.

Enrollment: 968 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:I(i) age ≥ 18 years and (ii) diagnosis of oHCM based on clinical and echocardiographic evaluation.

Exclusion Criteria: (i) a history of heart surgery (ii) Patients who had coronary atherosclerosis or myocardial infraction; (iii) Patients who had no angiography records.

Trial design

968 participants in 1 patient group

Obstructive hypertrophic cardiomyopathy who underwent septal myectomy

Description:

All patients underwent angiography and without other coronary artery disease.

Treatment:

Procedure: Coronary artery bypass grafting or unroofing