MYocardial DOmmages Related to COVID-19 (DOMY COVID)

University Hospital Center (CHU) Dijon Bourgogne

Status: Completed

Conditions: Non Ischemic Myocardial Injury; Troponin Elevation; Myocarditis; Covid19; Myocardial Infarction

Treatments: Biological: Biological data; Other: Clinical data

Study type: Observational

Funder types: Other

Identifiers

NCT04498065

COTTIN AOIc 2020

Details and patient eligibility

About

Myocardial injury, as assessed by elevation of cardiac troponins (Tnc), is frequent among patients with COVID-19. Although rare autopsy cases reported COVID-19 related myocardial inflammation, the origin of Tnc elevation is unknown to date. Several cardiac causes, such as myocarditis, non-ischemic myocardial injury (NIMI), or myocardial infarction (MI) may lead to Tnc kinetic. Our work will test the hypothesis that during SARS-Cov2 infection, the elevation of cardiac biomarkers could be linked to the occurrence of myocarditis.

Enrollment: 273 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COVID-19 positive patient hospitalized < 72 h after symptoms onset with troponin assessement.

Exclusion criteria

• patients hospitalized > 72h after symptom onset

Trial design

273 participants in 2 patient groups

A

Description:

COVID positive and Troponin positive

Treatment:

Biological: Biological data

Other: Clinical data

B

Description:

COVID positive and Troponin negative

Treatment:

Biological: Biological data

Other: Clinical data