Myocardial Involvement of Severe Acute Respiratory Syndrome-Cov-2 (Covid19) Infected Patients (COCARDE)

Toulouse University Hospital

Status: Completed

Conditions: Cardiomyopathies

Treatments: Diagnostic Test: Global Longitudinal Strain

Study type: Observational

Funder types: Other

Identifiers

NCT04358952

RC31/20/0117

2020-A00852-37 (Other Identifier)

Details and patient eligibility

About

The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown. Epidemiological studies report biological myocardial involvement in 10 to 25% of cases. The objective of this study is to cardiac phenotype using comprehensive cardiac imaging tools of patients infected with Covid 19 in order to explore the functional impact of the infection on the myocardium.

Full description

A large population of Covid 19 infected patients of different ages and severity levels will be explored by transthoracic echocardiography with measurement of myocardial functional parameters such as ejection fraction, longitudinal strain and relaxation parameters and will be compared to an uninfected population paired for age and sex.

Patients with biological myocardial involvement will be followed to determine the evolution of their myocardial functional parameters during the course of the infection.

Enrollment: 122 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR

Exclusion criteria

• Underage patients. Patients refusing to participate in research. Patients with a history of heart disease.

Trial design

122 participants in 1 patient group

COVID + patients

Description:

Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR

Treatment:

Diagnostic Test: Global Longitudinal Strain