Myocardial Oedema in ST Segment Elevation Myocardial Infarction Myocardial

Elisa McAlindon

Status: Completed

Conditions: ST Segment Elevation Myocardial Infarction; Myocardial Oedema

Treatments: Other: Cardiac magnetic resonance imaging

Study type: Observational

Funder types: Other

Identifiers

NCT01897350

Study 1953

Details and patient eligibility

About

Cardiac magnetic resonance imaging (CMR) is a non invasive technique used to obtain functional and anatomical information on the heart. Several CMR parameters measured after primary percutaneous coronary intervention (PPCI) have been shown to have prognostic value and are increasingly being used as surrogate endpoints in clinical trials. Myocardial oedema is a prognostic indicator following myocardial infarction1. Myocardial salvage is calculated as the myocardial oedema minus infarct size; this again is a prognostic indicator following STEMI. However, myocardial oedema imaging is controversial. There are multiple sequences available, with no standardisation of sequences used to assess this surrogate endpoint. The investigators propose to conduct a study to measure the myocardial oedema by all available techniques to determine the agreement between these methods.

Enrollment: 30 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• STEMI
• providing written informed consent

Exclusion criteria

• contraindication to CMR,
• atrial fibrillation,
• claustrophobia,
• eGFR < 30

Trial design

30 participants in 1 patient group

CMR following ST segment myocardial infarction

Treatment:

Other: Cardiac magnetic resonance imaging