Myocardial Perfusion Assessment With Multidetector Computed Tomography

Tennessee Heart and Vascular Institute, P.C.

Status and phase: Unknown; Phase 3

Conditions: Coronary Artery Disease

Treatments: Device: Regadenoson (Lexiscan) [muti-detector computed tomography]

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00846079

THVI-101

Details and patient eligibility

About

Demonstrate the ability of muti-detector computed tomography to adequately perform stress testing will result in a veritable "one-stop shop" of non-invasive cardiac imaging that is, the ability to directly visualize heart arteries with high accuracy and to simultaniously determine the hemodynamic significance of any blockages visualized.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults >18 years of age
• Adults undergoing myocardial perfusion SPECT imaging
• Adults with suspected coronary artery disease

Exclusion criteria

• Age <18
• Known or suspected renal insufficiency (Creatinine <1.7 mg/dl)
• Allergy to contrast
• Inability or contraindication to lexiscan or beta blocker

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)